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Zebra ZD421D Advanced Direct Thermal Desktop Label Printer

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Zebra ZD421D Direct Thermal Desktop Label Printers 


Engineered to be Easy and Secure

The Zebra ZD421D direct thermal advanced desktop printer is intuitive and frustration-free, for every user. With Print DNA and setup wizards, it's easy to install and start printing quickly. Manage on-site or remotely using the robust, web-based management tool. Use Print Touch with NFC to pair and print or access how-to-videos. Plus, Print Secure provides unmatched security for peace-of-mind protection. 

ZD421D | Flexibility

The Zebra ZD421D desktop label printer (DT) provides field upgradeable connectivity and media handling options to grow with your customer's business. This includes 802.11ac + Bluetooth, Ethernet and serial, peeler and cutter. Also, the battery and carrying case make these printers a transportable printing solution. 

Includes all the Right Features

The Zebra ZD421 advanced direct thermal label printer offers advanced features to set it apart, including five status LED icons and a 3-button user interface, movable sensor for greater media flexibility, fast print speeds, 300 or 74 meter ribbon capacity, PDF Direct, ZebraDesigner Essentials label designer, and optional 300 dpi resolution. The Zebra ZD421 is available in thermal transfer, direct thermal, healthcare and ribbon cartridge models, all backed by 2-year warranty. 

Zebra ZD421D | Speaks your Language

Deploy the Zebra ZD421 advanced direct thermal desktop printer into existing printer fleets with confidence. Supports both EPL and ZPL printer languages and can even be configured to emulate other printer languages using the Virtual Devices on-printer app, part of Zebra's Print DNA. And, customers can keep using their current label formats and applications - no modification needed.  

Ready for Tomorrow's Technology

Technology is constantly and rapidly advancing. Replacing outdated equipment is costly. Be ready for what's next with the intelligent printer that's engineered to evolve. The Zebra ZD421 desktop label printer includes a new innovative architecture to power ever-expanding printer capabilities.


Print Width

  • 4.09 in./104 mm for 203 dpi
  • 4.27 in./108 mm for 300 dpi

Print Resolution

  • 203 dpi/8 dots per mm
  • Optional 300 dpi/12 dots per mm (optional)

Maximum Speed

  • 6 in./152 mm per second (203 dpi)
  • 4 in./102 mm per second (300 dpi)

Media Sensors

  • Full width, moveable reflective/black mark sensor
  • Multi-position transmissive/gap sensor

Communication Methods

  • Field installable: Ethernet 10/100, 802.11ac Wi-Fi and Bluetooth 4.1 (dual radio); Serial RS-232 auto-sensing, DB-9
  • Factory installed: Ethernet 10/100, 802.11ac Wi-Fi and Bluetooth 4.1 (dual radio)

Key Features

  • Supports Zebra Print DNA tools
  • Compatible with any Windows, Android or iOS device
  • 3 control buttons, 5 status LEDs, movable media sensor
  • Max. print speed: 152 mm/sec. (203 dpi) or 102 mm/sec. (300 dpi)
  • Innovative 4 Inch desktop label printer in a variety of model options
1 to 10 of 10
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Zebra ZD421d Direct Thermal Desktop Printer - USB Bluetooth
Brand: Zebra
MPN: ZD4A042-D0EM00EZ
GTIN:5704174466970
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Zebra ZD421d, 8 dots/mm (203 dpi), USB, USB Host, BT (BLE) 
1 Each
from £290.20
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Zebra ZD421d Direct Thermal Desktop Printer - USB Bluetooth Wi-Fi
Brand: Zebra
MPN: ZD4A042-D0EW02EZ
GTIN:5704174524335
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Zebra ZD421d, 8 dots/mm (203 dpi), USB, USB Host, BT, Wi-Fi
1 Each
from £411.06
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Image of ZD4A042-D0EE00EZ
Zebra ZD421d Direct Thermal Desktop Printer - USB Bluetooth (BLE) and Ethernet
Brand: Zebra
MPN: ZD4A042-D0EE00EZ
GTIN:5704174463757
Bulk Pricing
Ready to Dispatch
Zebra ZD421d, 8 dots/mm (203 dpi), USB, USB Host, BT (BLE), Ethernet
1 Each
from £371.32
MultiBuy Pack of 5
Save 2.5%
MultiBuy Pack of 10
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Image of ZD4A043-D0EM00EZ
Zebra ZD421d Direct Thermal Desktop Printer - USB Bluetooth
Brand: Zebra
MPN: ZD4A043-D0EM00EZ
GTIN:5704174950363
Ready to Dispatch
Zebra ZD421d, 12 dots/mm (300 dpi), USB, USB Host, BT (BLE)
1 Each
from £350.63
MultiBuy Pack of 5
Save 2.5%
MultiBuy Pack of 10
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Zebra ZD421 Direct Thermal Desktop Printer - USB Wi-Fi
Brand: Zebra
MPN: ZD4A043-D0EW02EZ
GTIN:5704174547525
Ready To Dispatch
Zebra ZD421d, 12 dots/mm (300 dpi), USB, USB Host, BT, Wi-Fi
1 Each
from £471.50

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Zebra ZD421 Food Allergen Label Printer Starter Kit
Brand: Zebra
MPN: NATALAW-ZD421D-1-BTSE
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Natasha’s Law - Zebra ZD421 Food Allergen Labelling Starter Kit - Direct Thermal 200dpi
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from £581.67

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Zebra ZD421 Direct Thermal Desktop Printer - Healthcare - USB Bluetooth Ethernet
Brand: Zebra
MPN: ZD4AH43-D0EE00EZ
GTIN:5704174955252
Ready To Dispatch
Zebra ZD421d Healthcare, 12 dots/mm (300 dpi), USB, USB Host, BT (BLE), Ethernet, White
1 Each
from £510.05

Image of ZD4A043-D0EE00EZ
Zebra ZD421d Direct Thermal Desktop Printer - USB Bluetooth Ethernet
Brand: Zebra
MPN: ZD4A043-D0EE00EZ
GTIN:5704174531081
Ready To Dispatch
Zebra ZD421d, 12 dots/mm (300 dpi), USB, USB Host, BT (BLE), Ethernet
1 Each
from £428.69

Image of ZD4AH42-D0EW02EZ
Zebra ZD421 Direct Thermal Desktop Printer - Healthcare - USB Bluetooth Wi-Fi
Brand: Zebra
MPN: ZD4AH42-D0EW02EZ
Ready To Dispatch
Zebra ZD421d Healthcare, 8 dots/mm (203 dpi), USB, USB Host, BT, Wi-Fi, white
1 Each
from £501.66

Image of ZD4AH42-D0EE00EZ
Zebra ZD421 Direct Thermal Desktop Printer - Healthcare - USB Bluetooth Ethernet
Brand: Zebra
MPN: ZD4AH42-D0EE00EZ
GTIN:5704174977780
Ready To Dispatch
Zebra ZD421d Healthcare, 8 dots/mm (203 dpi), USB, USB Host, BT (BLE), Ethernet, white
1 Each
from £456.12

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